Patients undergoing routine inpatient surgery who have used antithrombotic medication before the operation.

This project focuses on the safe management of antithrombotic therapy in surgical patients. A “Perioperative Antithrombotic Medication Evaluation System” was developed through collaboration among the pharmacy department, IT office, and clinical teams. The system provides automated recommendations for drug discontinuation and resumption, with alerts covering preoperative evaluation, anesthesia consultation, postoperative resumption, and outpatient follow-up. Patients can also consult the pharmacy department or use an online platform for assistance. Following implementation, the preoperative screening rate increased from 58.6% to 100%, significantly enhancing medication safety. Standardized guidelines and visual educational materials further streamline workflows and improve patient adherence. This interdisciplinary model effectively balances bleeding and thromboembolism risks while improving clinical efficiency and patient safety.

An evidence-based and institutionally agreed “Perioperative Antithrombotic Medication Assessment System” was developed to provide automated recommendations for perioperative interruption and resumption of antithrombotic therapy.
The system automatically integrates patients’ thromboembolic history and procedure-specific bleeding risk to support physicians in preoperative risk assessment.
Visualized, patient-friendly guidance sheets for medication interruption and resumption are automatically generated, facilitating physician–patient communication.
From postoperative day 1 onward, the system performs medication resumption checks and sends reminders, safeguarding postoperative medication safety.

An average of 275 preoperative antithrombotic cases are identified monthly by the system.

The preoperative antithrombotic medication screening rate reached 100%.

The accuracy of perioperative antithrombotic medication interruption instructions was 96.5%.
The rate of antithrombotic medication resumption by postoperative day 3 reached 98.4%.

Institutional staff satisfaction with the system reached 100%.
Patient satisfaction reached 94%.

Participation in international clinical pharmacy knowledge-sharing activities to promote global exchange.
Through multidisciplinary collaboration, institutional guidelines were developed and integrated into a one-click system that generates perioperative antithrombotic medication interruption and resumption recommendations, achieving performance superior to international standards.
The project was presented at the 2025 EAHP (European Association of Hospital Pharmacists) Congress, and the manuscript is currently in preparation.

Standardized workflows and clinical guidelines were established to enhance consistency and safety in perioperative care.
An intelligent antithrombotic management platform was developed and successfully disseminated to multiple hospitals.
Visualized medication interruption and resumption instruction sheets effectively improved medication safety.
This initiative serves as a model for both domestic and international healthcare institutions, contributing to sustainable healthcare development by improving clinical efficiency and reducing adverse events.

Patients undergoing routine inpatient surgery who have used antithrombotic medication before the operation.

An evidence-based and institutionally agreed “Perioperative Antithrombotic Medication Assessment System” was developed to provide automated recommendations for perioperative interruption and resumption of antithrombotic therapy.
The system automatically integrates patients’ thromboembolic history and procedure-specific bleeding risk to support physicians in preoperative risk assessment.
Visualized, patient-friendly guidance sheets for medication interruption and resumption are automatically generated, facilitating physician–patient communication.
From postoperative day 1 onward, the system performs medication resumption checks and sends reminders, safeguarding postoperative medication safety.

An average of 275 preoperative antithrombotic cases are identified monthly by the system.

The preoperative antithrombotic medication screening rate reached 100%.

The accuracy of perioperative antithrombotic medication interruption instructions was 96.5%.
The rate of antithrombotic medication resumption by postoperative day 3 reached 98.4%.

Institutional staff satisfaction with the system reached 100%.
Patient satisfaction reached 94%.

Participation in international clinical pharmacy knowledge-sharing activities to promote global exchange.
Through multidisciplinary collaboration, institutional guidelines were developed and integrated into a one-click system that generates perioperative antithrombotic medication interruption and resumption recommendations, achieving performance superior to international standards.
The project was presented at the 2025 EAHP (European Association of Hospital Pharmacists) Congress, and the manuscript is currently in preparation.

Standardized workflows and clinical guidelines were established to enhance consistency and safety in perioperative care.
An intelligent antithrombotic management platform was developed and successfully disseminated to multiple hospitals.
Visualized medication interruption and resumption instruction sheets effectively improved medication safety.
This initiative serves as a model for both domestic and international healthcare institutions, contributing to sustainable healthcare development by improving clinical efficiency and reducing adverse events.