Insumate® bitter melon extract (containing patented sequenced 19 peptides) is a proprietary ingredient developed by Greenyn Biotechnology. It has received a No Objection Letter from the U.S. FDA for New Dietary Ingredient Notification (NDIN No. 1256). Insumate® is produced using a supercritical fluid extraction green process that recycles and reuses carbon dioxide, resulting in a low-molecular-weight sequenced peptide of only 2,162 Da, distinctly different from conventional hydrolyzed large-molecule bitter melon polypeptides. In addition to being featured in seven scientific publications, this innovative breakthrough has been awarded the Gold Medal at the Geneva International Exhibition of Inventions in Switzerland, the Gold Medal at the World Inventor Contest (WiC) in Korea, and the Gold Medal at the DAVINCI International Invention Expo (AII) in the United States. It has also been recognized with prestigious domestic awards, including the "National Invention and Creation Award" from the Ministry of Economic Affairs and the "National Innovation Award for Corporate Innovation" from the Biomedical Technology and Policy Research Center.

New Dietary Ingredient (NDI) Notification、Halal certification

Bitter Melon Extract 100%

製造廠名稱: Greenyn Biotechnology Co., Ltd. 製造廠登記: 66-005524, 製造廠品管: FSSC22000 HACCP ISO22000 其他(Certificate of GMP for Health Supplements, Certification of Food Sanitation and Safety Management systems, HALAL)

Monitoring of Critical Control Points (CCPs) in the manufacturing process 2.Regular implementation of the Environmental Monitoring Program (EMP) 3.Regular monitoring and management of vector, pest, and rodent control 4.Regular monitoring and management of employee hygiene 5.Regular monitoring and management of allergen control 6.Regular monitoring of measurement instruments and equipment

Regular inspection of the production self-checklist 2.Quality control and inspection reports for raw material procurement 3.Quality control and inspection reports for semi-finished products 4.Quality control and inspection reports for finished product shipments

Hsin-Yi Lo, Tin-Yun Ho, Chingju Lin, Chia-Cheng Li, and Chien-Yun Hsiang. Journal of Agricultural and Food Chemistry 2013 61 (10), 2461-2468 2. Hsin-Yi Lo, Tin-Yun Ho, Chia-Cheng Li, Jaw-Chyun Chen, Jau-Jin Liu, and Chien-Yun Hsiang. Journal of Agricultural and Food Chemistry 2014 62 (36), 8952-8961 3. Hsin-Yi Lo, Chia-Cheng Li, Tin-Yun Ho, Chien-Yun Hsiang. Food Chemistry, 2016 (204), 298-305 4. Frank Pan, Pang-Kuei Hsu, Wei-Hsiu Chang. Risk Manag Healthc Policy. 2020 20(13), 2219-2226 5. Pang-Kuei Hsu, Frank F C Pan, Ching-Sen Hsieh. Nutrients. 2020 12(5), 1252 6. Yi-Sun Yang, Nian-Yi Wu, Edy Kornelius, Chien-Ning Huang, Nae-Cherng Yang. Food Nutr Res. 2022 (3), 66 7. Liana L Guarneiri, Meredith L Wilcox, Chen-Meng Kuan, Kevin C Maki. J Am Nutr Assoc. 2024 (13), 1-9

1.US Patent US8476229B2 2.JP Patent JP6116539 3.TW Patent I342781 4.TW Patent I580690 5.TW Patent I593703 6.EU Patent EP2191837 (EU Cert.) 7.CH Patent EP2191837 (EU Cert.) 8.UK Patent EP2191837 (EU Cert.) 9.IT Patent EP2191837 (EU Cert.) 10.DE Patent EP2191837 (EU Cert.) 11.FR Patent EP2191837 (EU Cert.) 12.EU Patent EP2990050 (EU Cert.) 13.DE Patent EP2990050 (EU Cert.) 14.UK Patent EP2990050 (EU Cert.) 15.FR Patent EP2990050 (EU Cert.) 16.CH Patent EP2990050 (EU Cert.) 17.IT Patent EP2990050 (EU Cert.) 18.ES Patent EP2990050 (EU Cert.) 19.IE Patent EP2990050 (EU Cert.)